Vol. 42 | No. 1 | January-June 2014Back

Open Access

The Effectiveness of Omega-3 Polyunsaturated Fatty Acid Supplementation in Preventing Sudden Cardiac Death and Fatal Arrhythmias among Adult Coronary Artery Disease Patients: A Meta- analysis

Maria Blanca A. de Guzman, Sherrywin A. Simon, Marcellus Francis L. Ramirez
Jun 2014 DOI 10.69944/pjc.f381016945

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Maria Blanca A. de Guzman, MD, Sherrywin A. Simon, MD, Marcellus Francis L. Ramirez, MD

Section of Cardiology, Department of Medicine, University of Santo Tomas Hospital, Manila, Philippines 

 

References
  1. Fuster, V., Walsh, R., O’Rourke, R., Poole-Wilson. Chapter 57. Pathology of Myocardial Ischemia, Infarction, Reperfusion, and Sudden Death. In: Hurst’s The Heart, 12th Edition. The McGraw -Hill Companies,. 2008 
  2. Jan L. Breslow. N-3 Fatty acids and cardiovascular disease. Am J ClinNutr 2006;83(suppl):1477S-82S. 
  3. Leaf A, Kang JX, Xiao YF, Billman GE. Clinical prevention of sudden cardiac death by n_3 polyunsaturated fatty acids and mechanism of prevention of arrhythmias by n-3 fish oils. Circulation 2003;107:2646–52. 
  4. Campbell RW, Murray A, Julian DG. Ventricular arrhythmias in first 12 hours of acute myocardial infarction. Natural history study. Br Heart J 1981;46(4):351–357. 
  5. Perron AD, Sweeney T. Arrhythmic complications of acute coronary syndromes. Emerg Med Clin North Am 2005;23(4):1065–1082. 
  6. London B, Albert C, Anderson ME, Giles WR, Van Wagoner DR, Balk E, et al. Omega-3 fatty acids and car¬diac arrhythmias: prior studies and recommendations for future research: a report from the National Heart, Lung, and Blood Institute and Office Of Dietary Supplements Omega-3 Fatty Acids and their Role in Cardiac Arrhythmogenesis Workshop. Circulation. 2007;116: e320–e335. 
  7. Kromhout D, Bosschieter EB, de LezenneCoulander C. The inverse relation between fish consumption and 20-year mortality from coronary heart disease. N Engl J Med. 1985;312:1205–1209. 
  8. Burr ML, Fehily AM, Gilbert JF, Rogers S, Holliday RM, Sweetnam PM, et al. Effects of changes in fat, fish, and fibre intakes on death and myocardial reinfarction: Diet and Reinfarction Trial (DART). Lancet. 1989;2:757–761. 
  9. Daviglus ML, Stamler J, Orencia AJ, Dyer AR, Liu K, Greenland P, Walsh MK, Morris D, Shekelle RB. Fish consumption and the 30-year risk of fatal myocardial infarction. N Engl J Med. 1997;336:1046 –1053. 
  10. Albert CM, Hennekens CH, O’Donnel CJ, Ajani UA, Carey VJ, Willett, WC, Ruskin JN, Manson JE. Fish consumption and risk of sudden cardiac death. JAMA. 1998;279:23–28. 
  11. Albert CM, Campos H, Stampfer MJ, Ridker PM, Manson JE, Willett, WC, Ma J. Blood levels of long-chain n-3 fatty acids and the risk of sudden death. N Engl J Med. 2002;346:1113–1118. 
  12. GruppoItaliano per lo Studio della Sopravvivenza nell’Infarto Miocardico. Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial. Lancet. 1999;354:447–455. 
  13. Marchioli R, Barzi F, Bomba E, et al. Early protection against sudden death by n-3 polyunsaturated fatty acids after myocardial infarction: time-course analysis of the results of the GruppoItaliano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione. Circulation 2002;105:1897–1903. [PMID: 11997274] 
  14. Lavie CJ, Milani RV, Mehra MR, Ventura HO. Omega-3 polyunsaturated fatty acids and cardiovascular diseases. J Am Coll Cardiol. 2009;54:585–594. 
  15. Hu FB, Bronner L, Willett WC, et al. Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. JAMA 2002;287:1815–1821. 
  16. Kris-Etherton PM, Harris WS, Appel LJ. Fish consumption, fish oil, omega-3 fatty acids, and cardiovascular disease. Circulation 2002;106:2747–2757. 
  17. Lee KW, Lip GYH. The role of omega-3 fatty acids in the secondary prevention of cardiovascular disease: a Review. Q J Med 2003;96:465–480. 
  18. Hooper L, Thompson RL, Harrison RA, Summerbell CD, Ness AR, Moore HJ, et al. Risks and benefits of omega 3 fats for mortality, cardiovascular disease, and cancer: systematic review. BMJ 2006;332:752–760. 
  19. Brouwer IA, Zock PL, Camm AJ, Bocker D, Hauer RN, Wever EF, et al. Effect of fish oil on ventricular tachyarrhythmia and death in patients with implantable cardioverter defibrillators: the Study on Omega-3 Fatty Acids and Ventricular Arrhythmia (SOFA) randomized trial. JAMA. 2006;295:2613–2619. 
  20. Raitt MH, Connor WE, Morris C, Kron J, Halperin B, Chugh SS, et al. Fish oil supplementation and risk of ventricular tachycardia and ventricular fibrillation in patients with implantable defibrillators: a randomized controlled trial. JAMA. 2005;293:2884 –2891. 
  21. Saravanan P, Bridgewater B, West AL, O’Neill SC, Calder PC, Davidson NC. Omega-3 Fatty Acid Supplementation Does Not Reduce Risk of Atrial Fibrillation After Coronary Artery Bypass Surgery: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial. Circ Arrhythm Electrophysiol 2010;3:46-53. 
  22. Brouwer IA, Geelen A, Katan MB. N-3 Fatty acids, cardiac arrhythmia and fatal coronary heart disease. Progress Lipid Res 2006;45:357–367. 
  23. Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 2009;339:b2535. 
  24. Leaf A, Jorgensen MB, et al. Do fish oils prevent restenosis after coronary angioplasty? Circulation. 1994;90:2248-2257. 
  25. Singh RB, Niaz MA, Sharma JP, Kumar R, Rastogi V, Moshiri M. Randomized, double-blind, placebo-controlled trial of fish oil and mustard oil in patients with suspected acute myocardial infarction: the Indian experiment of infarct survival-4. Cardiovasc Drugs Ther. 1997;11(3):485-491. 
  26. Johansen O, Brekke M, Seljeflot I, Abdelnoor M, Arnesen H.N 3 fatty acids do not prevent restenosis after coronaryangioplasty: results from the CART study. Coronary Angioplasty Restenosis Trial. J Am Coll Cardiol. 1999;33:1619-26. 
  27. Nilsen DW, Albrektsen G, Landmark K, Moen S, Aarsland T, Woie L. Effects of a high-dose concentrate of n-3 fatty acids or corn oil introduced early after an acute myocardial infarction on serum triacylglycerol and HDL cholesterol. Am J Clin Nutr. 2001;74(1):50-56. 
  28. Leaf A, Albert CM, Josephson M, Steinhaus D, Kluger J, Kang JX, et al. Prevention of fatal arrhythmias in high-risk subjects by fish oil n-3 fatty acid intake (FAAT).Circulation. 2005;112:2762– 2768. 
  29. Yokoyama M, Origasa H,Matsuzaki M, Matsuzawa Y, Saito Y, Ishikawa Y, et al. Effects of eicosapentaenoic acid on major coronary events in hypercholesterolaemic patients (JELIS): a randomised open-label, blinded endpoint analysis. Lancet.2007;369:1090-8. 
  30. Rauch B, Schiele R, Schneider S, et al. OMEGA, a Randomized, Placebo-Controlled Trial to Test the Effect of Highly Purified Omega-3 Fatty Acids on Top of Modern Guideline-Adjusted Therapy After Myocardial Infarction. Circulation. 2010;122:2152- 2159. 
  31. Bosch J, Gerstein HC, Dagenais GR, et al; ORIGIN Trial Investigators. N-3 fatty acids and cardiovascular outcomes in patients with dysglycemia. N Engl J Med.2012; 367(4):309-318. 
  32. Coronel R, Wilms-Schopman FJ, Den Ruijter HM, Belterman CN,Schumacher CA, Opthof T, Hovenier R, Lemmens AG, Terpstra AH,Katan MB, Zock P. Dietary n-3 fatty acids promote arrhythmias during acute regional myocardial ischemia in isolated pig hearts. Cardiovasc Res 2007;73:386–394. 
  33. Jenkins DJ, Josse AR, Beyene J, Dorian P, Burr ML, LaBelle R, Kendall CW,Cunnane SC. Fish-oil supplementation in patients with implantable cardioverter defibrillators: a meta-analysis. CMAJ 2008;178:157–164.
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