Vol. 45 | No. 2 | July-December 2017Back

Open Access

Red Cell Distribution Width and Mortality in Patients with Acute Coronary Syndrome: A Meta-Analysis on Prognosis

More Info

Lauro L. Abrahan IV, MD; Elleen L. Cunanan, MD; John Daniel A. Ramos, MD; Marc Denver  A. Tiongson, MD

  1. Arbel Y, Birati EY, Finkelstein A, et al. Red blood cell distribution width and 3-year outcome in patients undergoing cardiac catheterization. J Thromb Thrombolysis. 2014 May;37(4):469-74.
  2. Aulakh R, Sohi I, Singh T, Kakkar N. Red cell distribution width (RDW) in the diagnosis of iron deficiency with microcytic hypochromic anemia. Indian J Pediatr. 2009 Mar;76(3):265-8.
  3. Viswanath D, Hegde R, Murthy V, Nagashree S, Shah R. Red cell distribution width in the diagnosis of iron deficiency anemia. Indian J Pediatr. 2001 Dec;68(12):1117-9.
  4. Buch AC, Karve PP, Panicker NK, Singru SA, Gupta SC. Role of red cell distribution width in classifying microcytic hypochromic anaemia. J Indian Med Assoc. 2011 May;109(5):297-9.
  5. Isik T, Uyarel H, Tanboga IH, et al. Relation of red cell distribution width with the presence, severity, and complexity of coronary artery disease. Coron Artery Dis 2012;23:51-6.
  6. Jia H, Li H, Zhang Y, et al. Association between red blood cell distribution width (RDW) and carotid artery atherosclerosis (CAS) in patients with primary ischemic stroke. Arch Gerontol Geriatr 2015;61:72-5.
  7. Kim J, Kim YD, Song TJ, et al. Red blood cell distribution width is associated with poor clinical outcome in acute cerebral infarction. Thromb Haemost 2012;108:349-56.
  8. Demirtas S, Karahan O, Yazici S, et al. The relationship between complete blood count parameters and Fontaine’s Stages in patients with peripheral arterial disease. Vascular 2014;22:427-31.
  9. Ye Z, Smith C, Kullo IJ. Usefulness of red cell distribution width to predict mortality in patients with peripheral artery disease. Am J Cardiol 2011;107:1241-5.
  10. Güngör B, Özcan KS, Erdinler , et al. Elevated levels of RDW is associated with non- valvular atrial fibrillation. J Thromb Thrombolysis 2014;37:404-10.
  11. Erta G, Aydin C, Sönmez O, et al. Red cell distribution width predicts new-onset atrial fibrillation after coronary artery bypass grafting. Scand Cardiovasc J 2013;47:132-5.
  12. Korantzopoulos P, Liu T. RDW as a marker of postoperative atrial fibrillation. Int J Cardiol 2015;191:109.
  13. Wan H, Yang Y, Zhu J, et al. The relationship between elevated red cell distribution width and long-term outcomes among patients with atrial fibrillation. Clin Biochem 2015;48:762-7.
  14. Felker GM, Allen LA, Pocock SJ, et al. Red cell distribution width as a novel prognostic marker in heart failure: data from the CHARM Program and the Duke Databank. J Am Coll Cardiol 2007;50:40-7.
  15. Huang YL, Hu ZD, Liu SJ, et al. Prognostic value of red blood cell distribution width for patients with heart failure: a systematic review and meta-analysis of cohort studies. PLoS One 2014;9:e104861.
  16. Wells GA, Shea B, O’Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta analyses. 2011. Available: http://www.ohri.ca/programs/clinical_ epidemiology/oxford.asp. Accessed January 9, 2017.
  17. Azab B, Torbey E, Hatoum H, et al. Usefulness of red cell distribution width in predicting all-cause long-term mortality after non-ST elevation myocardial infarction. Cardiology. 2011;119(2):72-80.
  18. Bekler A, Tenekecioğlu E, Erbağ G, et al. Relationship between red cell distribution width and long-term mortality in patients with non-ST elevation acute coronary syndrome. Anatol J Cardiol. 2015 Aug;15(8):634-9.
  19. Cavusoglu E, Chopra V, Gupta A, et al. Relation between red blood cell distribution width (RDW) and all-cause mortality at two years in an unselected population referred for coronary angiography. Int J Cardiol. 2010 May 28;141(2):141-6.
  20. Dabbah S, Hammerman H, Markiewicz W, Aronson D. Relation between red cell distribution width and clinical outcomes after acute myocardial infarction. Am J Cardiol. 2010 Feb 1;105(3):312-7.
  21. Ghaffari S, Pourafkari L, Sepehrvand N, et al. Red cell distribution width is a predictor of ST resolution and clinical outcome following thrombolysis in acute ST elevation myocardial infarction. Thromb Res. 2016 Apr;140:1-6.
  22. Gul M, Uyarel H, Ergelen M, et al. The relationship between red blood cell distribution width and the clinical outcomes in non-ST elevation myocardial infarction and unstable angina pectoris: 3-year follow-up. Coron Artery Dis. 2012 Aug;23(5):330-6.
  23. Ïlhan E, Güvenç TS, Altay S, et al. Predictive value of red cell distribution width in intrahospital mortality and postintervention thrombolysis in myocardial infarction flow in patients with acute anterior myocardial infarction. Coron Artery Dis. 2012 Nov;23(7):450-4.
  24. Isik T, Kurt M, Ayhan E, Tanboga IH, Ergelen M, Uyarel H. The impact of admission red cell distribution width on the development of poor myocardial perfusion after primary percutaneous intervention. Atherosclerosis. 2012 Sep;224(1):143-9.
  25. Sun XP, Chen WM, Sun ZJ, et al. Impact of red blood cell distribution width on long-term mortality in patients with ST elevation myocardial infarction. Cardiology. 2014;128(4):343-8.
  26. Turcato G, Serafini V, Dilda A, et al. Red blood cell distribution width independently predicts medium-term mortality and major adverse cardiac events after an acute coronary syndrome. Ann Transl Med. 2016 Jul;4(13):254.
  27. Uyarel H, Ergelen M, Cicek G, et al. Red cell distribution width as a novel prognostic marker in patients undergoing primary angioplasty for acute myocardial infarction. Coron Artery Dis. 2011 May;22(3):138-44.
  28. Wang YL, Hua Q, Bai CR, Tang Q. Relationship between red cell distribution width and short-term outcomes in acute syndrome in a Chinese population. Intern Med. 2011;50(24):2941- 5.
  29. Zorlu A, Yücel H, Kaya H, Korkmaz O, Yildirimli K, Bektasoglu G. Red cell distribution width (RDW) and increased risk of recurrent acute coronary syndrome. Acta Med Anatol. 2015;3(2):39-46.
  30. Su C, Liao LZ, Song Y, Xu ZW, Mei WY. The role of red blood cell distribution width in mortality and cardiovascular risk among patients with coronary artery diseases: a systematic review and meta analysis. Journal of Thoracic Disease 2014; 6(10): 1429-1440.
  31. Hansson GK. Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med. 2005 Apr 21;352(16):1685-95.
  32. Allen LA, Felker GM, Mehra MR, et al. Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure. J Card Fail. 2010 Mar;16(3):230-8.
  33. Y as JW, Horrow JC, Horne BD. Persistent increase in red cell size distribution width after acute diseases: A biomarker of hypoxemia? Clin Chim Acta 2015;448:107-17.
  34. Patel HH, Patel HR, Higgins JM. Modulation of red blood cell population dynamics is a fundamental homeostatic response to disease. Am J Hematol. 2015 May;90(5):422-8.
  35. Allen LA, Felker GM, Mehra MR, et al. Validation and potential mechanisms of red cell distribution width as a prognostic marker in heart failure. J Card Fail. 2010 Mar;16(3):230-8.

Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits use, share — copy and redistribute the material in any medium or format, adapt — remix, transform, and build upon the material, as long as you give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original. You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-sa/4.0/.