Vol. 50 | No. 2 | July-December 2022 Back

Open Access

Clinical and Angiographic Profile of Patients Undergoing Coronary Angiography at the Tertiary Hospital—A 19-Year Retrospective Observational Study

Abstract

INTRODUCTION: Coronary artery disease (CAD) is one of the leading causes of death globally.  Studies have shown association of CAD and its risk factors; however, data on association of  these risk factors and severity of CAD as seen in angiography in our local setting are still limited. 

OBJECTIVE: The aims of this study were to determine the clinical and angiographic profile  of patients who underwent coronary angiography, to correlate cardiovascular risk factors to  their angiographic findings, and to compare the trend of risk factors and angiography findings  between decades. 

METHODS: This is a retrospective observational study of patients aged 18 years or older,  of either sex, who underwent coronary angiography at a tertiary hospital from 2001 to 2019.  Pertinent risk factors were correlated with angiography findings to determine predictors for  significant CAD. 

RESULTS: The mean age of the patients was 58.6 years. There were more males (66%) than  females. The risk factors for the likelihood of significant CAD are older age (4.98% more for every  year increase in age), male sex (2.63 times), and diabetes mellitus (47.64%). The majority of the  patients had right dominant circulation, and significant lesions were more commonly seen in the  left anterior descending artery. There were statistically significant more patients with hypertension,  diabetes, and obesity in the present decade compared with the past. 

CONCLUSION: Increased age, male sex, and diabetes are associated with significant CAD in  the local setting. Diabetes must be aggressively controlled early to prevent the development of  significant CAD. 

KEYWORDS: coronary artery disease, risk factors, profile, coronary angiography

  1. Narayanaswamy G, Kshetrimayum S, Sharma HD, Devi  KB, Manpang NN, Chongtham DS. Profile of patients  undergoing coronary angiography at tertiary care center in  Northeast India. J Med Soc 2019;33(1):28–32. 
  2. Registered Deaths in the Philippines, 2017, Republic of the  Philippines, Philippine Statistics Authority. Published June  10, 2019. https://psa.gov.ph/vital-statistics/id/138794.  Accessed June 19, 2020. 
  3. Ebasone PV, Dzudie A, Jean Claude Ambassa JC, et al.  Risk factor profile in patients who underwent coronary  angiography at the Shisong Cardiac Centre, Cameroon. J  Xiangya Med 2019;4. doi: 10.21037/jxym.2019.06.01. 
  4. Peacock JL, Peacock PJ. Research design. In: Oxford  Handbook of Medical Statistics. New York: Oxford  University Press; 2011:60–61. 
  5. Rosenthal R. The 50% coronary stenosis. Am J Cardiol 2015;115(8):1162–1165. 
  6. Yusuf S, Hawken S, Ounpuu S, et al. Effect of potentially  modifiable risk factors associated with myocardial infarction  in 52 countries (the INTERHEART study): case control  study. Lancet 2004;364(9438):937–952. 
  7. Steyn K, Sliwa K, Hawken S, et al. Risk factors  associated with myocardial infarction in Africa. Circulation 2005;112(23):3554–3561. 
  8. Deshmukh PP, Singh MM, Deshpande MA, Rajput AS.  Clinical and angiographic profile of very young adults  presenting with first acute myocardial infarction: data  from a tertiary care center in Central India. Indian Heart J 2019;71(5):418–421. 
  9. Rosendorff C, Lackland D, Allison M, et al. Treatment  of hypertension in patients with coronary artery  disease. Hypertension 2015;65(6):1372–1407. 
  10. Ettehad D, Emdin C, Kiran A, et al. Blood pressure  lowering for prevention of cardiovascular disease and  death: a systematic review and meta-analysis. Lancet 2016;387(10022):957–967. 
  11. Mehta A. Managing hypertension in coronary artery  disease. Hypertension J 2020;6(2):87–93. 
  12. Wu TG, Wang L. Angiographic characteristics of the  coronary artery in patients with type 2 diabetes. Exp  Clin Cardiol 2002;7(4):199–200. 
  13. Zipes DP, Libby P, Bonow RO, et al, eds. Braunwald’s  Heart Disease: A Textbook of Cardiovascular Medicine.  11th ed. Philadelphia, PA: Elsevier Inc; 2019. 
  14. Moscucci M. Grossman & Baim’s Cardiac Catheterization,  Angiography, and Intervention. 8th ed. Philadelphia, PA:  Wolters Kluwer; 2014. 
  15. Zhou F, Liu Y, Ge P, et al. Coronary artery diameter is  inversely associated with the severity of coronary lesions  in patients undergoing coronary angiography. Cell Physiol  Biochem 2017;43(3):1247–1257. 
  16. Diabetes. 2021. https://www.who.int/news-room/fact sheets/detail/diabetes. Accessed March 23, 2021.
  17. Hypertension. 2021. https://www.who.int/news-room/fact sheets/detail/hypertension. Accessed March 23, 2021.
  18. Benjamin EJ, Muntner P, Alonso A, et al; on behalf of the  American Heart Association Council on Epidemiology and  Prevention Statistics Committee and Stroke Statistics  Subcommittee. Heart Disease and Stroke Statistics—2019  update. A report from the American Heart Association.  Circulation 2019;139:e56–e528. 
  19. Jasul G, Sy R; for the Philippine Association for the Study  of Overweight and Obesity (PASOO). Obesity treatment  recommendations in the Philippines: perspective on their  utility and implementation in clinical practice. J ASEAN Fed  Endocr Soc 2011;26(2). 

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