The Correlation of Platelet-to-Lymphocyte Ratio Levels With Clinical Outcomes in Acute Coronary Syndrome Patients Admitted in a Tertiary Hospital From January 2011 to December 2020
More Info
Jehaila B. Tenorio, MD | Brian Joseph M. Calinawagan, MD, FPCP,FPCC | Kara Kirsty V. Congjuico, MD
Silliman University Medical Center Foundation Inc, Dumaguete City, Negros Oriental, Philippines
Corresponding author:
Jehaila B. Tenorio, MD
Silliman University Medical Center Foundation Inc, Dumaguete City, Negros Oriental, Philippines
Email: jehailatenorio@gmail.com
Declaration of conflicts of interest: None.
- Loscalzo J, Fauci AS, Kasper DL, Hauser SL, Longo DL, Jameson JL. Harrison’s Principles of Internal Medicine. 21st ed. McGraw-Hill; 2022.
- Mapa DS. Causes of Deaths in the Philippines (Preliminary): January to June 2021. Philippine Statistics Authority. 2021. https://psa.gov.ph/content/causes-deaths-philippines preliminary-january-june2021. Accessed November 15, 2022.
- Libby P, Bonow RO, Mann DL, et al. Braunwald’s Heart Disease: A Textbook of Cardiovascular Medicine. 12th ed. Elsevier; 2021.
- Wang H, Liu Z, Shao J, et al. Immune and inflammation in acute coronary syndrome: molecular mechanisms and therapeutic implications. J Immunol Res 2020:4904217. https://doi.org/10.1155/2020/4904217.
- Massberg S, Schulz C, Gawaz M. Role of platelets in the pathophysiology of acute coronary syndrome. Semin Vasc Med 2003;3(2):147–162. https://doi. org/10.1055/s-2003-40673.
- Taleb S, Tedgui A, Mallat Z. Regulatory T-cell immunity and its relevance to atherosclerosis. J Intern Med 2008;263(5):489–499. https://doi.org/10.1111/j.1365- 2796.2008.01944.x.
- Bekler A, Gazi E, Yılmaz M, et al. Could elevated platelet lymphocyte ratio predict left ventricular systolic dysfunction in patients with non–ST elevated acute coronary syndrome? Anatolian J Cardiol 2015;15(5):385–390. https://doi.org/10.5152/akd.2014.5434.
- Yüksel M, Yıldız A, Oylumlu M, et al. The association between platelet/lymphocyte ratio and coronary artery disease severity. Anatolian J Cardiol 2015;15(8):640–647. https://doi.org/10.5152/akd.2014.5565.
- Oylumlu M, Yıldız A, Oylumlu M, et al. Platelet-to lymphocyte ratio is a predictor of in-hospital mortality patients with acute coronary syndrome. Anatolian J Cardiol 2015;15(4):277–283. https://doi.org/10.5152/ akd.2014.5366.
- Oylumlu M, Oylumlu M, Arslan B, et al. Platelet-to lymphocyte ratio is a predictor of long-term mortality in patients with acute coronary syndrome. Postepy Kardiol Interwencyjnej 2020;16(2):170–176. https://doi. org/10.5114/aic.2020.95859.
- Willim HA, Harianto JC, Cipta H. Platelet-to-lymphocyte ratio at admission as a predictor of in-hospital and long term outcomes in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a systematic review and meta analysis. Cardiol Res 2021;12(2):109–116. https://doi. org/10.14740/cr1219.
- Hudzik B, Szkodzinski J, Gorol J, et al. Platelet-to lymphocyte ratio is a marker of poor prognosis in patients with diabetes mellitus and ST-elevation myocardial infarction. Biomark Med 2015;9(3):199–207. https://doi. org/10.2217/bmm.14.100.
- Ugur M, Gul M, Bozbay M, et al. The relationship between platelet to lymphocyte ratio and the clinical outcomes in ST elevation myocardial infarction underwent primary coronary intervention. Blood Coagul Fibrinolysis 2014;25(8):806– 811. https://doi.org/10.1097/MBC.0000000000000150.
- Li L, Ma Y, Geng XB, et al. Platelet-to-lymphocyte ratio relates to poor prognosis in elderly patients with acute myocardial infarction. Aging Clin Exp Res 2021;33(3):619– 624. https://doi.org/10.1007/s40520-020-01555-7.
- Abrahan LL, Aherrera JM, Ramos JA, Reganit P, Punzalan F. Association of the platelet-lymphocyte ratio (PLR) with outcomes in patients admitted for acute coronary syndrome: the PLACS study. Philippine J Intern Med 2017;55(3):1–9.
- Zheng B, Huo Y, Lee SW, et al. Long-term antithrombotic management patterns in Asian patients with acute coronary syndrome: 2-year observations from the EPICOR Asia study. Clin Cardiol 2020;43(9), 999–1008. https://doi. org/10.1002/clc.23400.
- Zafrir B, Jaffe R, Skiman H, Barnett-Griness O, Saliba W. Lymphopenia and risk for long-term mortality among patients undergoing coronary angiography. Eur Heart J 2020;41(supplement_2):ehaa946.1340.
Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License, which permits use, share — copy and redistribute the material in any medium or format, adapt — remix, transform, and build upon the material, as long as you give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. You may not use the material for commercial purposes. If you remix, transform, or build upon the material, you must distribute your contributions under the same license as the original. You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by-nc-sa/4.0/.